Proposal Intel tracks deadlines, flags compliance risks, and generates draft-ready narratives for federal grant programs — so researchers and startups can focus on the science.
From NIH R01s to NSF SBIR Phase I, Proposal Intel maps your research profile against active solicitations and surfaces the highest-fit opportunities first.
Proposal Intel tracks NOT-OD-25-132 compliance including the 6-application annual cap. Deadline alerts, study section alignment, and score analysis from past cycles.
Up to $500K/yr (R01)NSF's AI transparency policy requires disclosure of any AI-generated content. Proposal Intel auto-flags AI-assisted sections and prepares your disclosure statement.
Up to $2M (Phase II)Coordinates your SBIR portfolio across NIH, NSF, DOD, and DOE. Tracks phase transitions, commercialization milestones, and agency-specific technical volume requirements.
Phase I: $150K–$275KARPA-E TEAMER, DOE Office of Science grants, and clean energy R&D solicitations. Technology readiness level matching and cost-share requirement tracking.
$500K–$3M+ (ARPA-E)Federal grant deadlines are notoriously unforgiving. One missed registration window or expired DUNS number kills a submission. Proposal Intel monitors every prerequisite, not just the final deadline.
Your research keywords, NAICS codes, and past submission history are matched against active FOAs and SBIRs daily.
AutomatedSAM.gov registration, eRA Commons account, Grants.gov registration — each has its own renewal cycle. All tracked.
Auto-checkedNotifies PIs, grants managers, and sponsored research offices — not just the platform admin.
Role-basedEvery federal grant program has unique formatting rules, disclosure requirements, and eligibility thresholds. Proposal Intel runs a compliance check before you submit — not after your deadline passes.
Effective September 25, 2025 — NIH now caps applications at 6 per PI per year across all mechanisms. Proposal Intel tracks your running count, flags programs where you're approaching the limit, and identifies co-PI substitution strategies to protect high-priority submissions.
Significance. Alzheimer's disease affects an estimated 6.9 million Americans aged 65 and older, with annual care costs projected to reach $360 billion by 2030 (Alzheimer's Association, 2024). Despite decades of research, no disease-modifying therapy has demonstrated efficacy in Phase III trials targeting amyloid clearance alone, suggesting that tau-mediated neurodegeneration represents an independent and understudied driver of cognitive decline.
Innovation. This project proposes the first application of cryo-EM-guided rational design to identify tau phosphorylation inhibitors selective for the AT8 epitope, which prior structural work in our laboratory has shown to adopt a conformation distinct from other tau isoforms implicated in non-AD tauopathies.
Approach. We will pursue three specific aims: (1) Characterize the structural basis of AT8 epitope-selective binding using cryo-EM at sub-3Å resolution; (2) Develop and validate lead compounds using in vitro tau aggregation assays; (3) Assess pharmacokinetic profile and CNS penetrance in transgenic mouse models.
Proposal Intel generates structured first drafts from your prior publications, biosketches, and the FOA's specific requirements — not generic templates. You edit, not start from scratch.
Upload your biosketch, prior publications, and project abstracts. The platform builds your research profile automatically.
One-time setupEach section of the narrative is mapped to the funding opportunity's review criteria and scoring rubric.
Per-applicationAI-generated content is labeled for NSF/NIH disclosure requirements. Page counts update in real time as you edit.
Agency-specific rulesBefore submission, score your application against the agency's review criteria using a simulated study section panel.
Pre-submission QASee how Proposal Intel fits your current grant portfolio and where compliance gaps are putting your funding at risk.